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Sunday, July 19, 2020 | History

1 edition of Molecular Determinants of Radiation Response found in the catalog.

Molecular Determinants of Radiation Response

Theodore L. DeWeese

Molecular Determinants of Radiation Response

by Theodore L. DeWeese

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Published by Springer Science+Business Media, LLC in New York, NY .
Written in English

    Subjects:
  • Medicine,
  • Toxicology,
  • Oncology

  • Edition Notes

    Statementedited by Theodore L. DeWeese, Marikki Laiho
    SeriesCurrent Cancer Research
    ContributionsLaiho, Marikki, SpringerLink (Online service)
    The Physical Object
    Format[electronic resource] /
    ID Numbers
    Open LibraryOL25561878M
    ISBN 109781441980434, 9781441980441

      Browse the archive of articles on Nature. Over the p years, the residence time and amount of soil carbon stored in the Ganges–Brahmaputra basin have been controlled by the intensity of. The molecular bases of radiation pathology, recovery, and antiradiation protection of the organism are considered. Low-Dose Radiation Cataract and Genetic Determinants of Radiosensitivity. Technical Report Kleiman, Norman Jay. The lens of the eye is one of the most radiosensitive tissues in the body. Ocular ionizing radiation exposure.

    UCLA; PMID "Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors." (Mellinghoff IK, N Engl J Med. Nov 10;(19)) Summary of biologic markers: EGFR gene amplification. Molecular Determinants of Radiation Response This book reviews a number of these important topics and will serve to provide a review of key basic and translational aspects of each. We have divided the book into two general categories for the purpose of organization: (1) Molecular Basis of DNA Damage Responses, and (2) Modulation of.

    The Columbia University Center for Radiological Research (CRR) was founded more than 75 years ago to better understand the human health risks associated with exposure to ionizing radiation exposure. It is the oldest and largest such research center in the world. The Center's efforts are focused on unraveling the biological and molecular mechanisms underlying radiation effects in cells, tissues.   The genome of the model moss Physcomitrella patens, which grows in sun-exposed open areas, encodes signaling and metabolic components that are implicated in the UV-B response in flowering plants. In this study, we describe the response of P. patens to UV-B radiation at the morphological and molecular levels.


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Molecular Determinants of Radiation Response by Theodore L. DeWeese Download PDF EPUB FB2

Molecular Determinants of Radiation Response includes chapters by expert authors who detail the present understanding of key DNA damage response pathways and proteins. The chapters include comprehensive discussions on where and how specific alterations in function of these pathways and proteins Molecular Determinants of Radiation Response book in substantive modifications of cellular.

ISBN: X: OCLC Number: Description: xiv, pages: illustrations. Contents: Molecular Determinants of Radiation Response Editors: Theodore L. DeWeese, M.D. and Marikki Laiho, M.D., Ph.D.

Molecular Basis of the DNA Damage Responses 1) H2AX in DNA Damage Response Christophe E. Redon, Jennifer S. Dickey.

Molecular Determinants of Radiation Response includes chapters by expert authors who detail the present understanding of key DNA damage response pathways and proteins. The chapters include comprehensive discussions on where and how specific alterations. Molecular Determinants of Radiation Response includes chapters by expert authors who detail the present understanding of key DNA damage response pathways and proteins.

The chapters include comprehensive discussions on where and how specific alterations in function of these pathways and proteins result in substantive modifications of cellular Author: Theodore L. DeWeese. Get this from a library. Molecular determinants of radiation response.

[Theodore L DeWeese; Marikki Laiho;] -- The DNA of mammalian cells is constantly under assault from both endogenous and exogenous sources.¡ Ionizing radiation is one of the most important sources of.

Molecular Determinants of Radiation Response. / DeWeese, Theodore L.; Laiho, Marikki. 1 ed. Springer, p. Research output: Book/Report › Anthology or special issue › Scientific › peer-review.

Molecular Determinants of Radiation Response includes chapters by expert authors who detail the present understanding of key DNA damage response pathways and proteins.

The chapters include comprehensive discussions on where and how specific alterations in function of these pathways and proteins result in substantive modifications of cellular Brand: Springer New York.

Non–small cell lung cancers are now recognized to contain considerable heterogeneity and molecular diversity. Substantial progress has been made regarding molecular determinants of response to targeted agents in advanced lung cancer, and recent findings have revealed subsets of patients with driver mutations that respond rapidly to selective by: 5.

Molecular and Genomic Determinants of Response to Immune Checkpoint Inhibition in Cancer Article in Annual Review of Medicine 69(1) February with 55 Reads How we measure 'reads'.

Molecular Determinants of Radiation Response in Non–Small Cell Lung Cancer Article in Seminars in radiation oncology 25(2) December with 87 Reads How we measure 'reads'.

Molecular Determinants of Radiation Response. ISBN e-ISBN Molecular Radiation Sciences Johns Hopkins University School of Medicine, North Broadway neoplastic transformation, and cancer therapy.

This book reviews a number of these important topics and will serve to provide a review of key basic. Several strategies have demonstrated antitumor activity in early-stage trials, and at least two have progressed to phase 3.

Future developments will be driven by a better understanding of the radiation response and molecular basis for tumor : Svend O. Freytag, Kenneth N. Barton, Farzan Siddiqui, Mohamed Elshaikh, Hans Stricker, Benjamin Movs.

Background: Rectal cancers are clinically different from colon cancers and have not yet been molecularly characterized due to the scarcity of pretreatment specimens. Discovery of molecular determinants of response to chemotherapy and radiation in patients with locally advanced rectal cancer (LARC, stage II and III) are needed to select those who can avoid surgery and benefit from watch-and Author: Walid Khaled Chatila, Michael Marco, Xuan Qu, Henry S.

Walch, Anisha Luthra, Chin-Tung Chen, Ritika. The Division of Translational Oncology was created to spearhead basic and translational research within the Department of Radiation Oncology. The goals of the division are to accelerate discoveries in the lab pertaining to cancer genomics, radiogenomics, genomic instability, and mechanisms of cellular response to radiation and other cancer therapeutics.

DOI: /JCO_suppl Journal of Clinical Oncology - published online before print Immune and molecular determinants of response to neoadjuvant chemotherapy in inflammatory breast cancer. Cited by: 2. Cell Physiology Source Book A Molecular Approach. Book • 3rd The molecular determinants of inactivation of the voltage-gated Na + channel have been well studied and have been shown Some also use the metabolic intermediates to modulate more distal processes n their scheme of stimulus-response coupling.

The fifth cell makes use of. To date, relatively little is known about the molecular response of bryophytes to UV-B radiation, which might be due to the general view of bryophytes as being shade adapted. However, many mosses, like the model organism Physcomitrella patens, grow in unshaded habitats exposed to high light and UV-B radiation intensities (Rensing et al., ).Cited by: 1.

Author(s): DeWeese,Theodore L; Laiho,Marikki Title(s): Molecular determinants of radiation response/ Theodore L. DeWeese, Marikki Laiho, editors. UV Responses: Molecular Interactions and Opportunities for Melanoma Prevention Erin M. Wolf Horrell and John A. D’Orazio Abstract UV radiation is a pervasive environmental agent that affects the skin in complex ways.

It benefits human health by its contribution to the biosynthesis of. Frankincense (Boswellia serrata, B. carterii) is used as traditional remedy to treat inflammatory diseases. The molecular effects of the active ingredients, the boswellic acids, on the immune system have previously been studied and verified in several clinical studies.

Boswellic acids also inhibit cancer cell growth in vitro and in vivo. The molecular basis of the cytotoxicity of boswellic Cited by: 9. Drought stress is a common adverse environmental condition that seriously affects crop productivity worldwide.

Due to the complexity of drought as a stress signal, deciphering drought tolerance mechanisms has remained a major challenge to plant biologists. To develop new approaches to study plant drought tolerance, we searched for phenotypes conferred by drought stress and identified the.The response of cancer patients to chemotherapy follows a very heterogeneous pattern.

Pharmacogenetics is the study of inherited differences in interindividual drug disposition and effects, with the goal of selecting the optimal drug therapy and dosage for each patient. Pharmacogenetics for cancer treatment is very significant, as cancer therapies exhibit severe systemic toxicity and Author: Munindra Ruwali.framework of the DFG-funded Research Training Group “Molecular determinants of the cellular radiation response and their potential for response modulation” (GRK).

The project will be performed with the clinical support of Dr. Petra Temming of the University Childrens Hospital Essen and Prof. Dr. Beate Timmermann, Head of the.